Vitamin K comprises a group of fat-soluble compounds. Several vitamin K-dependent proteins are involved in essential processes such as blood clotting, bone metabolism, and cardiovascular health. Vitamin K deficiency can contribute to significant bleeding, poor bone development, osteoporosis, and increased cardiovascular disease. According to the National Academy of Science Food and Nutrition In the late 1920s, through the efforts of a Swiss scientist named Karrer and his colleagues, the fat-soluble compound in liver was isolated and termed vitamin A . This topic review will focus on issues related to vitamin A. Overviews of the other fat-soluble vitamins, minerals, and water-soluble vitamins are available elsewhere. Bile acid deficiency in your small intestine leads to malabsorption of fats and fat-soluble vitamins (A, D, E and K). This can lead to malnutrition and specific problems related to fat-soluble vitamin deficiencies. For example, vitamin D deficiency affects your bones, and vitamin A deficiency affects your vision. Vitamin D deficiency 3. Vitamin D deficiency is one of the most common vitamin deficiencies. There are several causes, including lack of sunlight exposure, malnutrition (often from substance abuse), malabsorption disorders and chronic kidney disease. Clinically, untreated vitamin D deficiency manifests as osteomalacia in adults and rickets in Fat Soluble: The fat-soluble vitamins (A, D, E, and K) are absorbed with dietary fat. These vitamins then travel with dietary fats as part of chylomicrons through the bloodstream to reach body cells. Special carriers in the bloodstream help distribute some of these vitamins. Fat-soluble vitamins are stored mostly in the liver and fatty tissues. 9.3.1 Physiological Importance of Fat Soluble Vitamins The fat soluble vitamins perform a range of functions in the body. These are found both in plant and animal food sources. The dietary sources, physiological role, deficiency diseases and the hypervitaminosis symptoms of all the fat soluble vitamins are compiled in Table 9.1. The toxic effect of The liver is importantly involved in vitamin metabolism. The liver produces bile for absorption of fat-soluble vitamins (A, D, E, K), and the liver is an important site for vitamin storage. Vitamin A is stored in both stellate cells and hepatocytes. Approximately 95% of total body vitamin A is stored in the liver, representing a 1- to 2-year Excessive consumption of vitamins. Hypervitaminosis is a condition of abnormally high storage levels of vitamins, which can lead to various symptoms as over excitement, irritability, or even toxicity. Specific medical names of the different conditions are derived from the given vitamin involved: an excess of vitamin A, for example, is called Unabsorbed fats trap fat-soluble vitamins (A, D, E, K) and possibly some minerals, causing deficiency. Bacterial overgrowth results in deconjugation and dehydroxylation of bile salts, limiting the absorption of fats. Unabsorbed bile salts stimulate water secretion in the colon, causing diarrhea.

Abstract. Cystic fibrosis (CF) is a common disorder that effects the overall nutritional and fat-soluble vitamin intake of those who carry it. Fat-soluble vitamin deficiency and CF symptoms have a direct correlation with each other. Patients with CF need extra fat-soluble vitamins for additional nutritional intake as well as proper growth and

The best sources of fat-soluble vitamins include: Vitamin A: Found in potato, carrots, pumpkins, spinach, beef and eggs. Vitamin D: Found in fortified milk and other dairy products. Vitamin E: Found in fortified cereals, leafy green vegetables, seeds, and nuts. Vitamin K: Found in dark green leafy vegetables and in turnip or beet green.

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    • deficiency symptoms of fat soluble vitamins